Chiefs of Mission for Panama
- William Insco Buchanan (1903-1904)
- John Barrett (1904-1905)
- Charles Edward Magoon (1905-1906)
- Herbert Goldsmith Squiers (1906-1909)
- Robert Stockwell Reynolds Hitt (1909-1910)
- Thomas Cleland Dawson (1910-1910)
- Henry Percival Dodge (1911-1913)
- William Jennings Price (1913-1921)
- John Glover South (1921-1930)
- Roy Tasco Davis (1929-1933)
- Antonio Cornelius Gonzalez (1933-1935)
- George Thomas Summerlin (1934-)
- George Thomas Summerlin (1935-1937)
- Francis Patrick Corrigan (1937-1939)
- William Dawson (1939-1941)
- Edwin Carleton Wilson (1941-1943)
- Avra Milvin Warren (1944-1945)
- Raymond Henry Norweb (1945-)
- Frank Thomas Hines (1945-)
- Frank Thomas Hines (1945-1948)
- Monnett Bain Davis (1948-1951)
- John Cooper Wiley (1951-1953)
- Selden Chapin (1953-1955)
- Julian Fiske Harrington (1955-1960)
- Joseph Simpson Farland (1960-1963)
- Jack Hood Vaughn (1964-1965)
- Charles Wallace Adair (1965-1969)
- Robert Marion Sayre (1969-1974)
- Frank Townsend Bow (1972-)
- William John Jorden (1974-1978)
- Ambler Holmes Moss (1978-1982)
- Arthur H. Davis (1986-1990)
- Deane Roesch Hinton (1990-1994)
- William J. Hughes (1995-1998)
- Simon Ferro (1998-2001)
- Linda Ellen Watt (2002-2005)
- William A. Eaton (2005-2008)
- Barbara Jean Stephenson (2008-2010)
- Phyllis Marie Powers (2010-)
- Jonathan D. Farrar (2012-)
- Wallace Wyman Stuart (-)
- Robert A. Pastor (-)
- Henry Landes Taylor (-)